Neuro fibromatosis tumors

Neurofibromatosis (NF) is a genetic disorder that causes tumors to form on nerve tissues. These tumors can develop anywhere in the nervous system, including the brain, spinal cord, and nerves. The tumors are usually non-cancerous (benign) but can sometimes become cancerous (malignant).

There are three types of Neurofibromatosis:

1. Neurofibromatosis Type 1 (NF1) – More common, affects the skin and nerves.
2. Neurofibromatosis Type 2 (NF2) – Causes tumors on the nerves responsible for hearing and balance.
3. Schwannomatosis – A rare form that leads to painful nerve tumors.

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Causes of Neurofibromatosis:

🧬 Genetic Mutation – It is caused by mutations in the NF1, NF2, or SMARCB1/LZTR1 genes.
👪 Inherited Condition – 50% of cases are inherited from parents.
⚡ Spontaneous Mutation – In some cases, NF develops without a family history.

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Symptoms of Neurofibromatosis:

🟢 Neurofibromatosis Type 1 (NF1) Symptoms:
🔹 Café-au-lait spots – Light brown skin patches.
🔹 Neurofibromas – Soft, noncancerous skin tumors.
🔹 Lisch nodules – Tiny brown spots in the eyes.
🔹 Freckling in armpits/groin area – Appears in childhood.
🔹 Learning difficulties – ADHD, speech problems.
🔹 Bone deformities – Curved spine (scoliosis), bowing of legs.
🔹 Large head size (macrocephaly).
🔹 High blood pressure (hypertension).

🟠 Neurofibromatosis Type 2 (NF2) Symptoms:
🔹 Hearing loss – Due to tumors on auditory nerves.
🔹 Tinnitus (ringing in ears).
🔹 Balance problems & dizziness.
🔹 Cataracts (cloudy vision) at a young age.
🔹 Weakness in arms or legs (due to spinal tumors).

🔴 Schwannomatosis Symptoms (Rare & Severe Pain):
🔹 Painful nerve tumors (schwannomas).
🔹 Muscle weakness.
🔹 Tingling/numbness in different body parts.